My cat has squamous cell carcinoma | Dr. Justine Lee, DACVECC, DABT, Board-Certified Veterinary Specialist
If your cat was just diagnosed with squamous cell carcinoma (commonly abbreviated “SCC”), I can whole-heartedly empathize. In this blog, I share my own story, along with some important information for cat owners to know if their cat was just diagnosed with this horrible cancer.
My own 19-year-old cat, Seamus, was just recently diagnosed with SCC last month, and I’m heartbroken. Seamus was previously diagnosed with chronic kidney failure (CKF) and so I weighed him once a month for years. I wanted to make sure he maintained his weight. Well, last month, he lost 0.7 pounds, and I instantly knew something more severe was going on. That’s when I did a complete physical exam and found a fast growing tumor in his mouth.
I took him to our board-certified veterinary dentist at my specialty clinic, where he was sedated and put under general anesthesia for dental x-rays, lymph node aspirate (for cytology), extraction of tooth and biopsy of the mass. Unfortunately, days later, he was diagnosed with SCC on the biopsy and lymph node aspirate.
SCC is one of the most common cancers seen in cats, and accounts for approximately 10% of the type of cancers that cats get. Unfortunately, the most common location that cats get SCC is in the mouth, which is hard for pet owners to be able to “see” it. Unfortunately, this is a really rapid, fast-growing cancer and is very invasive (which means it grows into the nearby tissue and lymph nodes). While it rarely spreads to other parts of the body, it can grow so quickly and cause pain and discomfort that it prevents cats from eating. Often, cats will express interest in food – in other words – they’ll still come to the food bowl, but then they turn away or eat only a few bites before giving up due to oral pain. That’s why it’s so important to diagnose it as soon as possible so treatment can started immediately.
Clinical signs of SCC in cats include:
- Drooling (even discolored brown drool)
- Bad breath (halitosis)
- Weight loss
- Not eating
- Frequent tongue movement or licking
- Dropping food
- Swelling on the side of the jaw (resulting in asymmetry)
- Pain on opening the mouth
Unfortunately, any aged cat can get SCC, but in research studies, the average age was 12.5 years of age (range 3-21 years of age). Some studies have looked at environmental toxins like tobacco smoke having an increased risk for cats developing SCC. For cat owners who smoked 1-19 cigarettes a day, their cats had a statistically significant 4X increase in the risk of SCC compared to non-smoking households. (No, I don’t smoke, and even my cat got SCC). In another study, cats that wore flea collars also had a statistically significant 5X increased risk of SCC. The same study that evaluated smoke exposure also found an increase in SCC in cats that frequently ate canned cat food (compared to those that ate dry food). This may be related to the nutrient content of these foods, the chemicals used in canned food, or even the hypothesis that cats that ate dry food have less tartar buildup and less dental disease. There is some thought that chronic inflammation or chronic dental disease may be a causative predisposing factor for SCC.
Diagnosis of SCC is typically based on:
- Oral exam
- Physical examination
- Blood work (as an elevated calcium level can sometimes be seen)
- Dental x-rays (which typically need to be done under general anesthesia) which may show a “lytic” or eaten away appearance to the bone
- Biopsy (which needs to be done under general anesthesia)
- Cytology of the lymph node (where a small needle is used to aspirate cells out)
- X-rays of the chest to make sure cancer hasn’t spread elsewhere
Treatment
Unfortunately, there isn’t much treatment or advances with treating SCC in cats, as it’s so aggressive. While surgery and radiation therapy can be considered, along with chemotherapy, they have been often unsuccessful with a poor long term survival. Only 10% of cats survive to 1 year, with most cats surviving an average of 3 months even with aggressive therapy. Without treatment, the average survival is only about one month.
So, what did I do as a veterinary specialist when my cat was diagnosed?
My goal was to preserve his quality of life. To spoil him. To make each surviving day a good quality of life where Seamus was happy. That meant keeping him on pain medications (such as buprenorphine and gabapentin). Since the mass is in the mouth, it’s often hard to pill your cat. And as my cat had a really painful mouth, I elected to use Simbadol (which is a once a day injection that lasts 24 hours) – your veterinarian will have to administer this, but it can be used for a few days initially to help. I also used a long acting antibiotic injection called Convenia for 2 weeks (1 injection, 7 days apart), as I was worried that there was a bacterial infection in his mouth from the decaying cancer tissue.
Lastly, canned food and cat treats…whatever Seamus wanted to eat. Here, my favorite treats that he loved:
- Bonito flakes
- Gerber Meat-based baby food
(e.g., chicken, turkey, chicken/veggie blends)
- Canned tuna in water
- Shrimp (frozen shrimp that was microwaved to cook it)
- Greenies cat treats
- Royal Canin Savory food
(e.g., chicken, turkey, chicken/veggie blends)
What about prevention?
While SCC is aggressive, the sooner it is found and the smaller it is at the time of diagnosis, the more treatment options are available. That’s one of the reasons why daily dental home care, regular oral exams and regular dental cleaning increase the chances of finding SCC early. When in doubt, talk to your veterinarian about this, as dental health is so important!
Most importantly, consider humane euthanasia when you feel like your cat’s quality of life is deteriorating. For me, the signs below indicate a poor quality of life. When in doubt, talk to your veterinarian.
- Not eating for 2 days in a row
- Continued weight loss
- Hiding
- Not moving
- Difficulty breathing
- Sleeping all the time
I wish I had better news for you. I’m right there with you, heartbroken with my old man. When in doubt, talk to a board-certified veterinary dentist or veterinary oncologist for more information… and hugs to your cat. This veterinarian’s thinking of you.
More information can be found here at Cornell’s website. Further information for your veterinarian (with links to the studies) can be found at DVM360.
Thank you for this post. My cat was just diagnosed and I, too, am heartbroken and feel lost. I plan to spoil him unconditionally until his time comes, and even though I know euthanasia is the humane course of action, the thought of saying goodbye is tearing me apart. It’s nice to hear the perspective of a professional in the veterinary field who also dealt with this in their personal life.
My heart goes out to you and your cat. It’s a terrible disease but my cat was very happy until the very end… talk to your vet about pain medication options to keep your cat eating and comfortable for the last few weeks. Prayers for you guys. Best, Dr. Justine Lee
Hello Dr Lee. Today was a bad day. I’ve been crying since noon and I still am and it’s 2:00 am. “T-Meow” is a cool masculine Louisiana cat that got into my soul 15 1/2 years ago. He swims with me in our pool, he opens doors and walks on in, and rides in the truck with his head out the window. I speak to him everyday in a language of our own. And “Gris Gris”, our other cat rides his coattail. My heart is breaking and I can’t stop it. I feel your pain. But part of me can’t let go without a fight. Because I Beleive that he could be the one who beats this. I would be so grateful if you could direct me to an oncologist or surgeon. Or a holistic dr who treats without or before chemo, for consultation. I’m impressed with your creditials. I mean no disrespect to you. I’m so lost. ..thank you for your blog.
I’m so sorry to hear that Keith. YOu can find an oncologist in your area here:
https://www.acvim.org/
Thank you, Dr Lee, for this comforting and compassionate post. I’m so sorry you lost your Seamus. My sweet Eddie is on my lap now. Her tumor is in her skull below her eye, but other than the bulging, she seems totally fine. Her symptoms first showed up as abscessed teeth, and she lost a lot of weight before we were able to get them removed & treated. Since the teeth came out, though, she’s been eating like a pig, jumping out the window onto the roof, meowing at all hours of the day & night, and generally acting like a contented. Perversely, she really loves extra scratchies right on the boniest part of the tumor. I wish now more than ever I could talk to her & discuss her options. The act of giving her buprenorphine or any other oral medicine seems to traumatize her more than whatever pain she may be in. Should I stop with the meds & just give extra tumor scratches? I don’t know! We will, however, keep feeding her “human tuna” for the duration, because that definitely makes her happy.
My heart is with all the cats who bear this diagnosis and with the humans who love them. Best wishes, everyone!
I’m so sorry to hear this. 🙁 Talk to your vet about the 24 hour lasting buprenorphine, Simbadol, and they can give it once a day. Otherwise, just under the tongue really quickly at home should work. You can also ask about a long acting antibiotic (Convenia) so you don’t have to medicate her. Try tuna benito flakes + tuna and spoil her as much as you can!
Deepest sympathies,
Dr. Justine Lee
This post has been so helpful. Feels like this is the first post from someone knowledgeable who’s actually seeing what I’m seeing. Heartbroken. My little one got diagnosed just over a week ago. Today is the first day of her barely eating. Yesterday she ate some of her favorite food (mashed) pretty normally.
She’s been hiding periodically throughout the day for a few days and I can feel the lump getting a little bigger. Tonight I just scheduled an appointment for in-home euthanasia but could only get it for Tuesday morning (it’s Saturday morning). I worry that she’ll be in pain but I don’t want her last moments to be in fear, hence the in-home service. She’s on my lap right now. Such a sweet girl.
I’m babbling. Thanks for listening.
I’m so sorry to hear that. Keep her happy and keep tempting her to eat! Thinking of you guys.
Best,
Dr. Justine Lee
My cat Ruby was just diagnosed a week ago. She only turned 5 in April. My one male cat just had to be our down yesterday due to a blood clot in his lungs. He was 9. I’m so heart broken because it will leave my 3rd cat who is 8 all alone until we’re both ready to get a new friend. My vet put Ruby under and removed the mass and some teeth to make eating more comfortable for her. I know there’s no cure or solution. Right now she’s on pain meds and antibiotics. I keep crying because losing 2 so close together is so incredibly hard. I keep hoping that him removing a large amount of the mass will give her some more time. Do you believe it will? I’m just so terrified of losing her.
Sadly, even with “debulking’ removal, it typically only allows about a 1-2 month survival. However, the benefit of removal is that it’ll help immediately and allows for biopsy which is imperative!
My guy was diagnosed today… and has had symptoms for a few weeks. The vet gave him steroids to help with pain. He is still so happy and constantly wanting attention. He also has an ulcer in his mouth so it bleeds slightly… the vet recommended to wait to see how bad it is with the biopsy(he did a FNA and looked to diagnose) and sutured the ulcer.. but I feel like I should have put him down. But then I feel like I’m giving up on him since he is so incredibly happy. I know some time next week will be the time because I don’t want him to start suffering. It’s just very hard
I’m so sorry. I will say that I rarely have an owner regret euthanizing too early when it comes to cancer…
Should I even wait for the biopsy then? The vet said he saw a large tumor under the tongue which was causing the deviation… he still wants a lot of attention but he’s a small cat anyway so his weight loss is significant on him. My vet said let’s wait for the biopsy then speak about options but I just don’t know what to do. I feel like he is still a happy cat but he isn’t the same. I know I wanted at least the weekend to say my goodbyes
Tiffany, how are you and how is your kitty? would love to share my story with you
Dr. Lee,
Thank you for sharing your touching story and such a lovely cat. Our cat Chloe was diagnosed in May this year and the mass under her tongue grew to 1cm (by June) where she could no longer use her tongue to eat. She was otherwise still energetic, engaged, and in good spirits. When we noticed her unable to eat on her own, we immediately started feeding her with a syringe and only give her pate wet food that she loves and eats 2-3x/day which we squeeze little by little with the plastic syringe. As you mention above, as long as we’re seeing she’s happy and engaged, we will continue to feed with the syringe, lots of love, playing, and massages. We give her pain med and antibiotic as needed and the Vet also gave us anti-inflammatory. Did you administer anti-inflammatory? What are you thoughts on anti-inflam medicine (metacam)? Many many thanks for your insight.
My guy was diagnosed in early May and I think we’re coming to the end soon. He’s having trouble eating. And started bleeding within the last week. Im having trouble with the fact that I know I’ll have to make the call soon, but he still snuggles and purrs and loves laying in the sun. I just don’t know how long to wait.
My Moses was diagnosed in early May and I know we’re coming to the end soon. He’s having trouble eating and he’s started bleeding within the last week. Sometimes he seems frustrated that he can’t get this thing off of his chin. I know I’ll have to make the call soon, but he still loves snuggles and he purrs and loves laying in the sun. I just don’t know how long to wait.
Dr. Lee,
Thank you for sharing your touching story and such a lovely cat. Our cat Chloe was diagnosed in May this year and the mass under her tongue grew to 1cm (by June) where she could no longer use her tongue to eat. She was otherwise still energetic, engaged, and in good spirits. When we noticed her unable to eat on her own, we immediately started feeding her with a syringe and only give her pate wet food that she loves and eats 2-3x/day which we squeeze little by little with the plastic syringe. As you mention above, as long as we’re seeing she’s happy and engaged, we will continue to feed with the syringe, lots of love, playing, and massages. We give her pain med and antibiotic as needed and the Vet also gave us anti-inflammatory. Did you administer anti-inflammatory? What are you thoughts on anti-inflam medicine (metacam)? Many many thanks for your insight.
I’d make sure to use buprenorphine/buprenex for pain. I typically don’t use Metacam chronically, but as SCC is end stage and survival is typically only 5 weeks, I think it’s ok as long as the kidney function is normal! I’d check with your vet to be safe! Best of luck and prayers for Chloe.
Thank you for your response! Another thing we are considering as Chloe is eating less and less, is to have the vet set up a esophageal tube for feeding her. What are your thoughts on tube feeding at this stage of the disease (Chloe was diagnosed in early May).
Thanks,
Philippe & Sandra
I do prefer feeding tubes over syringe feeding, honestly, as it’s much less stressful to your cat!
P.S. got a steroid shot a few days ago at the 2nd opinion appointment, and a bag full of buprenorphine I give every 12 hours. At initial diagnosis 8 days ago I got antibiotics which I think definitely cleared up the infection. It all happened so fast. I scratch her under her chin every day (she loves it) and there was no lump two weeks ago.
This post really resonated with me.
Our cat Minzi was diagnosed with this horrible cancer about 13 months ago, and she is still alive, which seems uncommon based on what I have been reading.
She did initially have the tumour in her upper jaw removed, but then 4 months later (in January this year), it was back.
Since then it has gradually turned into a huge growth affecting the whole left side of her face, leaving her unable to eat by her herself. So my wife and I have been hand-feeding her with cat treats (one by one) for months now already. It’s a time-consuming process, making sure she can catch each treat with her teeth and chew it, rather than the treat falling out of her mouth again.
She has been on steroids and medication to stop bleeding since the beginning of the year.
She is lethargic and now spends practically 24/7 in the same place, where she feels safe, except for mornings and evenings, when it’s meal time for us, and she expresses her desire to drink water from the running tap and be fed, though the amount she is eating has decreased significantly especially in the last week or so.
I feel that we have come to a point where she has no qualitiy of life left anymore, and it’s time to end her suffering and allow her to have a peaceful end by putting her to sleep.
However, my wife believes that since she does not show any obvious signs of being in pain, and still shows an appetite, it proves that she still has a will to live, and it’s not our right to ‘play God’. Her intention is to let nature run its course and wait for her to die naturally.
It’s a touchy subject, and I’m completely stressed out over this situation, unable to know what to do. It just breaks my heart seeing our furbaby like this every day, and getting weaker with each day.
Any views?
Oh man, it’s such a hard decision. I would keep her on buprenorphine for pain control and an appetite stimulant. If she’s not eating and seems painful, I’d recommend putting her to sleep. She won’t die naturally or peacefully at home, and will just slowly waste away. It’s so hard, but euthanasia is a gift, and I’ve never had a pet owner regret putting to sleep to early, but rather, waiting too long…
I hope that helps and my heart goes out to you.
Best,
Dr. Justine Lee
Thanks for the input, which basically confirms what I think is the right thing to do. Convincing my wife will be an entirely different matter, though.
Thanks for this post. I’ve been googling for days to get some real life info and this really helped. My guy is 18, and he’s such a part of our family. He grew old as my four girls grew up. He’s had some minor issues and weight loss for a couple of months but only found tumors Friday when his jaw seemed to to crooked out of nowhere and literally overnight. My hope is for him to make it through Christmas. He is eating wet food, and other than seeming more tired, he has moments of his usual spunk and seems normal. The smell is awful but the kids don’t care. He is getting non stop love and just like you said, we are spoiling him and loving him as much as we can. I won’t call euthanasia until I know he can no longer eat or has some other signs of pain. Taking it a day at a time and hoping that we will get a few more days with him. I’ve been a mess, so thank you for your post bc it was like it was written by me. It helped.
I’m so sorry – thinking of you and your old man, and make the last few days to weeks icing on the cake! Milk, canned tuna water, whatever he wants! Talk to your vet about bpurenex for pain medication.
My cat Furby has this awful disease too. He is 20 years old. He’s starting to sneeze mucus and cough a lot now, and I’m wondering if he’s probably in pain. He tries to eat soft food, but cannot without choking. Hard food is a bit better. I am at a loss of knowing when do I let him go.
I’m so sorry about everyone’s cats. My cat Mia was diagnosed with a tumor on the right side of her tongue 3 weeks ago. It is the deadly cancer squamous cell carcinoma. They gave her 2-6 weeks. She is declining but still can eat as long as its soft food. I give her Gerber Chicken baby food and cat fish/chicken snacks that I crush up. She hasn’t lost any weight yet. Mia also loves turkey deli meat smashed up. She is taking steroids and it seems to be working for the inflammation. Mia doesn’t seem like she is in pain. When she meows it seems to be not as loud, probably because her throat is closing up. She is not as active as before. She has an appetite because of the steroids. This is all heart wrenching to me. She was fine up until 4 weeks ago she wasn’t eating right and I saw her throw up blood and brought her to the vet. The worst night.
I am not sure when I should put her down. I want her to pass at home but I don’t want her to be in pain. I don’t think she is in pain. Her mind is all still there. My fear is that her throat will be closed up and she won’t be able to eat and I will have to bring her to the vet to put her down. Just the fear of Mia going to the vet would be horrible to her. She would look at me and say “mom, what are you doing to me”. I can’t stop crying about my poor Mia.
I’m so sorry, Mary. If it helps, I wrote this blog about the decision to euthanize here:
https://drjustinelee.com/for-love-of-dog-how-much-would-you-pay-for-your-dog-dr-justine-lee/
When in doubt, I always counsel people that I see people regretting euthanize TOO late, not too early. 🙁 It’s such a tough decision. There are appetite stimulants too to help.
Dr. Justine Lee
Thank you Dr. Lee and everyone who has posted. I, too, have been looking for something other than technical explanations of this condition and this site has been very helpful. My experience is similar to everyone who has posted. Our cat Smudge was diagnosed with oral SCC about 3 weeks ago. He started having trouble eating his dry food (fed in morning) but no trouble with canned food (fed in evening). I scheduled a dental exam/cleaning but a week before the procedure I could see he was very uncomfortable, took him to the vet for quick exam and pain meds and they moved his dental up. At the dental the Dr. felt a mass under his tongue (now making his tongue stick out most of the time) and the xrays of left lower jaw looked bad. Biopsy was positive for SCC. He’s on meloxicam every third day and buprenorphine every 12 hours. We’ve adjusted his drugs based on his behavior. The day he gets his meloxicam are his best days but he’s good the other 2 days acting like he always has except sleeping a little more. We’re feeding him a smooth pate cat food with some water added to make it easier for him to eat. He really wants dry food and after experimenting we now give him a morning snack by crushing the dry pieces into granules and adding a little water and putting it into a small bowl with steep sides so he can push it into his mouth easier. Vet says we can increase the meloxicam dose when needed and increase the buprenorphine to every 8 hours when needed. We will keep him comfortable and spoiled as long as we can. I hope this helps others trying to find a way to support and comfort their best friend.